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Drug Facts :: About Drug Classes and Schedules

Updated July 2010

People in a variety of drug-related settings will need to know the legal status of various substances. This has implications for the legal possession, storage and supply of such substances. However, the majority of sites and literature only make reference to the most frequently encountered controlled drugs. This leaves workers uncertain as to whether drugs they encounter are not actually controlled drugs, or simply haven't been listed.

Drugs are "controlled" primarily by two linked pieces of legislation: the Misuse of Drugs Act which groups drugs by Class, and the Misuse of Drugs Regulations, which lists them by Schedule. The Classes of drugs, Class A, B, C defines the penalties for each group of drugs. The Schedules within the Misuse of Drugs Regulations describe the rules for possession, production and supply of each drug.

The following lists are comprehensive lists of drugs controlled under the Misuse of Drugs Act and described under the Medicines Act.

The original Misuse of Drugs Act 1971 can be viewed here.

There have been numerous changes to the legislation since; some have changed the powers within the act, or linked to the act. But the most frequent changes have been the addition of drugs to the list of Controlled Drugs or changes to their Class.

This situation hasn't been helped because there isn't a single "official" published accessible list of drugs Controlled under the Misuse of Drugs Act 1971.

The most up-to-date version is online here but, shockingly, has not been updated to reflect amendments since 2003, meaning a string of changes are not incorporated in to it.

Many of these changes are introduced by Statutory Instruments, but again, with no single list of SIs which have been applied to the Act, it is hard to be sure what changes have been introduced.

Different SIs need to be used to change the Misuse of Drugs Act and the Misuse of Drugs Regulations. The database of Statutory Instruments is here, and you can use the year/number (e.g. 2010/1143) to look up each SI.

The final element which makes the situation still more confusing is that whereas drugs were once generally added by name, they increasingly need to be added in broad groups, to cover potentially new drugs which are molecularly tweaked to bypass the legislation. Legislation is increasingly written in very broad terms to catch these molecular variants. While this ensures more drugs are covered by each clause it does make some of the legislation unintelligible. It also leaves confusion as to if some drugs are covered by the legislation or not.

In order to try and rectify this situation, KFx has posted an updated list of drugs controlled by Class and Schedule. This is built on the framework of the 1971 Act (as ammended) on the UK Statute Law Database and then incorporates SIs which have changed the Class of drugs.

In order to see which legislation introduced which changes, all changes are colour coded. Drugs which have been added or moved are shown in a colour, and at the end of the Drug Classes, a colour coded list of Statutory Instruments shows which legislation introduced this change.

The page lists drugs by class and by schedule seperately. The lists are alphabetical.

Drug Facts List

Drug Facts:

Quick links to information below:

Classes: Class A | Class B | Class C

Schedules: Schedule 1 | Schedule 2 | Schedule 3 | Schedule 4(i) | Schedule 4(ii) | Schedule 5

Misuse of Drugs Act 1971: Drug Classes

Misuse of Drugs Act, Schedule 2: Controlled Drugs

PART 1

Class A Drugs

1. The following substances and products, namely:

(a)

Acetorphine
Alfentanil
Allylprodine
Alphacetylmethadol
Alphameprodine
Alphamethadol
Alphaprodine
Anileridine

Benzethidine
Benzylmorphine (3-benzyl morphine) Betacetylmethadol
Betameprodme
Betamethadol
Betaprodine
Bezitramide
Bufotenine

Carfentanil
Clonitazene
Coca leaf
Cocaine

Desomorphine
Dextromoramide
Diamorphine
Diampromide
Diethylthiambutene
Difenoxin (l-(3-cyano-3,3-diphenyl propyl)-4-
-4-phenylpiperidine-4-carboxylic acid
Dihydrocodeinone O-carboxymethyloxime
Dihydroetorphine
Dihydromorphine
Dimenoxadole
Dimepheptanol
Dimethylthiambutene
Dioxaphetyl butytate
Diphenoxylate
Dipipanone
Drotebanol (3,4-dimethoxy-17-methylmorphinan-6ß,14-diol)

Ecgonine, and any derivative ofecgonine which is convertible to ecgonine or to cocaine
Ethylmethylthiambutene
Eticyclidine
Etonitazene
Etorphine
Etoxeridine
Etryptamine

Fentanyl
Furethidine

Hydrocodone
Hydromorphinol
Hydromorphone
Hydroxypethidine

Isomethadone

Ketobemidone

Levomethorphan
Levomoramide
Levophenacylmorphan
Levorphanol
Lofentanil
Lysergamide
Lysergide and other N-alkyi derivatives of lysergamide

Mescaline
Metazocine
Methadone
Methadyl acetate
Methylamphetamine
Methyldesorphin
Methyldihydromorphine(6-methyldihydromorphine)
Metopon
Morpheridine
Morphine
Morphine methobromide, morphine N-oxide and other pentavalent nitrogen morphine derivatives
Myrophine

Nicomorphine (3,6-dinicotinoylmorphine)
Noracymethadol
Norlevorphanol
Normethadone
Normorphine
Norpipanone

Opium, whether raw, prepared or medicinal
Oxycodone
Oxymorphone

Pethidine
Phenadoxone
Phenampromide
Phenazocine
Phencyclidine
Phenomorphail
Phenoperidine
Piminodine
Piritramide
Poppy-straw .and concentrate of poppy-straw
Proheptazine
Properidine (l-methyl-4-phenvl piperidine-4-carboxylic acidI is. propyi ester) Psilocin

Racemethorphan
Remifentanil
Racemoramide
Racemorphan
Rolicyclidine

Sufentanil

Tenocyclidine
Thebacon
Thebaine
Tilidate
Trimeperidine

4-Bromo-2,5-dimethoxy-x-methyl-phenethylamine
4-Cyano-2-dimethylamino-4,4-di-phenylbutane
4-Cyano-l-methyl-4-phenyl-piperidine
N,N-Diethyltryptamine
N,N-Dimenthyltryptamine
1 2,5-Dimethoxy-x-4-dimethylphenethylamine
N-Hydroxy-tenamphetamine
1-Methyl-4-phenylpiperidine4-carboxylic acid
2-Methyl-3-morpholino-1,1 diphenylpropanecarboxylic acid . 4-Methylaminorex
4-Phenylpiperidine-4-carboxylic acid ethylester

(b) any compound (not being a compound for the time being specified in sub-paragraph (a) above) structurally derived from tryptamine or from a ring-hydroxy tryptamine by substitution at the nitrogen atom of the sidechain with one or more alkyl substituents but no other substituent;

(ba) the following phenethylamine derivatives, namely:

Allyl(a-methyl-3,4-methylenedioxyphenethyl)amine
2-Amino-1-(2,5-dimethoxy-4-methylphenyl)ethanol
2-Amino-1-(3,4-dimethoxyphenyl)ethanol
Benzyl(a-methyl-3,4-methylenedioxyphenethyl)amine
4-Bromo-ß,2,5-trimethoxyphenethylamine
N-(4-sec-Butylthio-2,5-dimethoxyphenethyl)hydroxylamine
Cyclopropylmethyl(a-methyl-3,4-methylenedioxyphenethyl)amine
2-(4,7-Dimethoxy-2,3-dihydro-1H-indan-5-yl)ethylamine
2-(4,7-Dimethoxy-2,3-dihydro-1H-indan-5-yl)-1-methylethylamine
2-(2,5-Dimethoxy-4-methylphenyl)cyclopropylamine
2-(1,4-Dimethoxy-2-naphthyl)ethylamine
2-(1,4-Dimethoxy-2-naphthyl)-1-methylethylamine
N-(2,5-Dimethoxy-4-propylthiophenethyl)hydroxylamine
2-(1,4-Dimethoxy-5,6,7,8-tetrahydro-2-naphthyl)ethylamine
2-(1,4-Dimethoxy-5,6,7,8-tetrahydro-2-naphthyl)-1-methylethylamine
a,a-Dimethyl-3,4-methylenedioxyphenethylamine
a,a-Dimethyl-3,4-methylenedioxyphenethyl(methyl)amine
Dimethyl(a-methyl-3,4-methylenedioxyphenethyl)amine
N-(4-Ethylthio-2,5-dimethoxyphenethyl)hydroxylamine
4-Iodo-2,5-dimethoxy-a-methylphenethyl(dimethyl)amine
2-(1,4-Methano-5,8-dimethoxy-1,2,3,4-tetrahydro-6-naphthyl)ethylamine
2-(1,4-Methano-5,8-dimethoxy-1,2,3,4-tetrahydro-6-naphthyl)-1-methylethylamine
2-(5-Methoxy-2,2-dimethyl-2,3-dihydrobenzo[b]furan-6-yl)-1-methylethylamine
2-Methoxyethyl(a-methyl-3,4-methylenedioxyphenethyl)amine
2-(5-Methoxy-2-methyl-2,3-dihydrobenzo[b]furan-6-yl)-1-methylethylamine
ß-Methoxy-3,4-methylenedioxyphenethylamine
1-(3,4-Methylenedioxybenzyl)butyl(ethyl)amine
1-(3,4-Methylenedioxybenzyl)butyl(methyl)amine
2-(a-Methyl-3,4-methylenedioxyphenethylamino)ethanol
a-Methyl-3,4-methylenedioxyphenethyl(prop-2-ynyl)amine
N-Methyl-N-(a-methyl-3,4-methylenedioxyphenethyl)hydroxylamine
O-Methyl-N-(a-methyl-3,4-methylenedioxyphenethyl)hydroxylamine
a-Methyl-4-(methylthio)phenethylamine
ß,3,4,5-Tetramethoxyphenethylamine
ß,2,5-Trimethoxy-4-methylphenethylamine

(c) any compound (not being methoxyphenamine or a compound for the time being specified in sub-paragraph (a) above) structurally derived from phenethylamine anN-alkylphenethylamine,a-methylphenethylamine, anN-alkyl-a-methylphenethylamine,a-ethylphenethylamine, or anN-alkyl-a-ethylphenethylamine by substitution in the ring to any extent with alkyl, alkoxy, alkylenedioxy or halide substituents, whether or not further substituted in the ring by one or more other univalent substituents.]

(d) any compound (not being a compound for the time being specified in sub-paragraph (a) above) structurally derived from fentanyl by modification in any of the following ways, that is to say,

(e) any compound (not being a compound for the time being specified in sub-paragraph (a) above) structurally derived from pethidine by modification in any of the following ways, that is to say,

2. Any stereoisomeric form of a substance for the time being specified in paragraph 1 above not being dextromethorphan or dextrorphan.

3. Any ester or ether of a substance for the time being specified in paragraph 1 or 2 above [F51 not being a substance for the time being specified in Part II of this Schedule].

4. Any salt of a substance for the time being specified in any of paragraphs 1 to 3 above.

5. Any preparation or other product containing a substance or product for the time being specified in any of paragraphs 1 to 4 above.

6. Any preparation designed for administration by injection which includes a substance or product for the time being specified in any of paragraphs 1 to 3 of Part II of this Schedule.

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PART II

Class B drugs

1. The following substances and products, namely:

(a)

Acetylhydrocodeine
Amphetamine

Cannabis and cannabis resin
Cannabinol
Cannabinol Derivatives

Codeine

Dihydrocodeine

Ethylmorphine (3-EEthylmorphine)

Glutethimide

Lefetamine

Mecloqualone
Methaqualone
Methcathinone
4–Methylmethcathinone
a-Methylphenethylhydroxylamine
Methylphenidate
Methylphenobarbitone

Nicocodine
Nicodicodine (6-nicotinoyl-dihydrocodeine)
Norcodeine

Pentazocine
Phenmetrazine
Pholcodine
Propiram

Zipeprol

(aa) Any compound (not being bupropion, cathinone, diethylpropion, pyrovalerone or a compound for the time being specified in sub–paragraph (a) above) structurally derived from 2–amino–1–phenyl–1–propanone by modification in any of the following ways, that is to say,

(ab) Any compound structurally derived from 2–aminopropan–1–one by substitution at the 1-position with any monocyclic, or fused-polycyclic ring system (not being a phenyl ring or alkylenedioxyphenyl ring system), whether or not the compound is further modified in any of the following ways, that is to say, .

(b) any 5,5 disubstituted barbituric acid.

(c) [2,3–Dihydro–5–methyl–3–(4–morpholinylmethyl)pyrrolo[1, 2, 3–de]–1,4–benzoxazin–6–yl]–1–naphthalenylmethanone.

3–Dimethylheptyl–11–hydroxyhexahydrocannabinol.

[9–Hydroxy–6–methyl–3–[5–phenylpentan–2–yl] oxy–5, 6, 6a, 7, 8, 9, 10, 10a–octahydrophenanthridin–1–yl] acetate.

9-(Hydroxymethyl)–6, 6–dimethyl–3–(2–methyloctan–2–yl)–6a, 7, 10, 10a–tetrahydrobenzo[c]chromen–1–ol.

Nabilone.

Any compound structurally derived from 3–(1–naphthoyl)indole or 1H–indol–3–yl–(1–naphthyl)methane by substitution at the nitrogen atom of the indole ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent.

Any compound structurally derived from 3–(1–naphthoyl)pyrrole by substitution at the nitrogen atom of the pyrrole ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the pyrrole ring to any extent and whether or not substituted in the naphthyl ring to any extent.

Any compound structurally derived from 1–(1–naphthylmethyl)indene by substitution at the 3–position of the indene ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent.

Any compound structurally derived from 3–phenylacetylindole by substitution at the nitrogen atom of the indole ring with alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent.

Any compound structurally derived from 2–(3–hydroxycyclohexyl)phenol by substitution at the 5–position of the phenolic ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the cyclohexyl ring to any extent.

2. Any stereoisomeric form of a substance for the time being specified in paragraph 1 of this Part of this Schedule.

2a. Any ester or ether of cannabinol or of a cannabinol derivative or of a substance for the time being specified in paragraph 1(c) of this Part of this Schedule

3. Any salt of a substance for the time being specified in paragraph 1 or 2 or 2A of this Part of this Schedule.

4. Any preparation or other product containing a substance or product for the time being specified in any of paragraphs 1 to 3 of this Part of this Schedule, not being a preparation falling within paragraph 6 of Part I of this Schedule.

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PART III

Class C drugs

1: The following substances and products, namely:

(a)

Alprazolam
Aminorex

Benzphetamine
Bromazepam
Brotizolam
Buprenorphine

Camazepam
Cathine
Cathinone
Chlordiazepoxide
Chlorphentermine
Clobazam
Clonazepam
Clorazepic Acid
Clotiazepam
Cloxazolam

Delorazepam
Dextropropoxyphene
Diazepam
Diethylproprion

Estazolam
Ethchlorvynol
Ethinamate
Ethyl loflazepate

Fencamfamin
Fenethylline
Fenproporex
Flucliazepam
Flunitrazepam
Flurazepam

Gamma-butyrolactone

Halazepam
Haloxazolam
4-hydroxy-n-butyric acid

Ketamine
Ketazolam

Loprazolam
Lorazepam
Lormetazepam

Mazindol
Medazepam
Mefenorex
Mephentermine
Meprobamate
Mesocarb

Methyprylone
Midazolam

Nimetazepam
Nitrazepam
Nordazepam

Oxazepam
Oxazolam

Pemoline
Phendimetrazine
Phentermine
Pinazepam
Pipadrol
Prazepam
Pyrovalerone

Temazepam
Tetrazepam
Triazolam

N-Ethylamphetamine

Zolpidem

(b)

Atamestane
5a–Androstane–3,17–diol
Androst-4-ene-3,17-diol
1–Androstenediol
1–Androstenedione

4-Androstene-3, 17-dione
5–Androstenedione
5-Androstene-3, 17-diol

Bolandiol
Bolasterone
Bolazine
Boldenone
Boldione
Bolenol
Bolmantalate
1,4–Butanediol

Calusterone
4-Chloromethandienone
Clostebol

Danazol
Desoxymethyltestosterone

Drostanolone

Enestebol
Epitiostanol
Ethyloestrenol

Fluoxymesterone
Formebolone
Furazabol

Gestrinone

3–Hydroxy–5a–androstan–17–one

Mebolazine
Mepitiostane
Mesabolone
Mestanolone
Mesterolone
Methandienone
Methandriol
Methenolone
Methyltestosterone
Metribolone
Mibolerone

Nandrolone
19–Norandrostenedione
19-Nor-4-Androstene-3, 17-dione 19-Nor-5-Androstene-3, 17-diol
19–Norandrosterone
Norboletone
Norclostebol
Norethandrolone
19–Noretiocholanolone

Oripavine
Ovandrotone
Oxabolone
Oxandrolone
Oxymesterone
Oxymetholone

Prasterone
Propetandrol
Prostanozol

Quinbolone

Roxibolone

Silandrone
Stanolone
Stanozolol
Stenbolone

Testosterone
Tetrahydrogestrinone
Thiomesterone
Trenbolone

(c) any compound (not being Trilostane or a compound for the time being specified in sub-paragraph (b) above) structurally derived from 17-hydroxyandrostan-3-one or from 17-hydroxyestran-3-one by modification in any of the following ways, that is to say,

(ca) 1–benzylpiperazine or any compound structurally derived from 1–benzylpiperazine or 1–phenylpiperazine by modification in any of the following ways:

(d) any substance which is an ester or ether (or, where more than one hydroxyl function is available, both an ester and an ether) of a substance specified in sub-paragraph (b) or described in sub-paragraph (c) above;

(e) Chorionic Gonadotrophin (HCG).
Clenbuterol.
Non-human chorionic gonadotrophin.
Somatotropin.
Somatrem.
Somatropin
Zeranol
Zilpaterol

2. Any stereoisomeric form of a substance for the time being specified in paragraph 1 of this Part of this Schedule [not being phenylpropanolamine.]

3. Any salt of a substance for the time being specified in paragraph 1 or 2 of this Part of this Schedule.

4. Any preparation or other product containing a substance for the time being specified in any of paragraphs 1 to 3 of this Part of this Schedule.

Meaning of certain Expressions used in this Schedule

For the purposes of this Schedule the following expressions (which are not among those defined in section 37(1) of this Act) have the meanings hereby assigned to them respectively, that is to say:

Amendment to the Misuse of Drugs Act by Statutory Instrument

The colours below are linked to the drug entries in the tables and lists above to make it easy to see which drugs were added by which SI in the tables above.

SI2001/3932
This Order adds thirty-six substances to Schedule 2 to the Misuse of Drugs Act 1971 which specifies drugs which are subject to control under the Act. The thirty-six substances are phenethylamine derivatives which are not covered by the definition in paragraph 1(c) of Part I of Schedule 2 to the 1971 Act. Thirty-five of the substances are added as Class A drugs; and a-Methylphenethylhydroxylamine is added as a Class B drug.

SI2003/1243
This Order adds eight substances to Schedule 2 to the Misuse of Drugs Act 1971 which specifies drugs which are subject to control under the Act. Two of the substances, Dihydroetorphine and Remifentanil, are added as Class A drugs; and the remaining six, 4-Androstene-3, 17-dione; 5-Androstene-3, 17-diol; 4-Hydroxy-n-butyric acid; 19-Nor-4-Androstene-3; 17-dione, 19-Nor-5-Androstene-13, 17-diol and Zolpidem, are added as Class C drugs.

SI2005/3178
This Order inserts Ketamine into Part 3 of Schedule 2 to the Misuse of Drugs Act 1971, which specifies drugs which are subject to control under that Act as Class C drugs.

SI2006/3331
This Order reclassifies methylamphetamine, previously a Class B drug, as a Class A drug by moving it from Part 2 of Schedule 2 to the Misuse of Drugs Act 1971 to Part 1 of that Schedule.

SI2008/3130
This Order reclassifies cannabis, cannabis resin, cannabinol and cannabinol derivatives from Class C to Class B drugs for the purposes of control under the Misuse of Drugs Act 1971. In addition, any substance which is an ester or ether of cannabinol or of a cannabinol derivative is reclassified as a Class B drug.

SI2009/3209
This Order adds synthetic cannabinoid receptor agonists to Part 2 of Schedule 2 to the Misuse of Drugs Act 1971 (“the Act”) which specifies drugs which are subject to control as Class B drugs under the Act. In addition, the Order adds Gamma-butyrolactone (GBL), 1,4–butanediol (1,4–BD), 15 anabolic steroids, two non-steroidal agents, Oripavine, 1–benzylpiperazine (BZP) and a group of substituted piperazines to Part 3 of Schedule 2 to the Act which specifies drugs which are subject to control as Class C drugs under the Act.

SI2010/1207
This Order adds 4-methylmethcathinone (commonly known as mephedrone) and other cathinone derivatives to Part 2 of Schedule 2 to the Misuse of Drugs Act 1971 (“the Act”) which specifies drugs which are subject to control as Class B drugs under the Act. It does not include cathinones and cathinone derivatives already controlled under the Act or bupropion.

SI2010/1833
This Order adds a further group of cathinone derivatives (including naphthylpyrovalerone, commonly known as naphyrone) to Part 2 of Schedule 2 to the Misuse of Drugs Act 1971 which specifies drugs which are subject to control as Class B drugs under that Act.

Misuse Of Drugs Regulations 2001

Drug Schedules

The Misuse of Drugs Regulations (1985) with various amendments were reviewed and rationalised. The end result was a revised set of regulations that came into force on February 1st 2002. The revised regulations, as introduced by SI2001/3998 form the basis of the tables below and can be viewed here.

Since 2001, the Misuse of Drugs Regulations 2001 have been further amended by SI; some of these concerned the regulations themselves while others added new drugs to the Schedules. Where drugs have been added to the schedules since 2005, these are indicated on the tables below in colour. The relevant Statutory Instrument which introduced the change is listed at the bottom in the same colour with its explanatory note.

The Misuse of Drugs Regulations creates 5 Schedules, governing possession and supply of the drugs controlled under the Misuse of Drugs Act. The regulations also govern prescribing, safe custody, importation, exportation, production and record keeping.

When considering who can possess or supply Controlled Drugs (CDs), it is more important to look at the Schedule of the drug, rather than the Class. The Class determines how dangerous a drug is perceived to be, and penalties relating to the drug. The Schedule defines who may be in possession of or supply each drug, and under what conditions.

For an understanding of the requirements related to each schedule as applicable in lay-settings please consult the LEGISLATION document in the Resources section.

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Schedule 1

CONTROLLED DRUGS SUBJECT TO THE REQUIREMENTS OF REGULATIONS 14, 15, 16, 18, 19, 20, 23, 26 AND 27

1. The following substances and products, namely -

(a) Bufotenine
1,4-Butanediol
Cannabinol
Cannabinol derivatives not being dronabinol or its stereoisomers
Cannabis and cannabis resin
Cathinone
Coca leaf
Concentrate of poppy-straw
2,3–Dihydro–5–methyl–3–(4–morpholinylmethyl)pyrrolo[1, 2, 3–de]–1,4–benzoxazin–6–yl]–1–naphthalenylmethanone
3–Dimethylheptyl–11–hydroxyhexahydrocannabinol

Eticyclidine
Etryptamine
Fungus (of any kind) which contains psilocin or an ester of psilocin
Gamma-butyrolactone
[9–Hydroxy–6–methyl–3–[5–phenylpentan–2–yl] oxy–5, 6, 6a, 7, 8, 9, 10, 10a–octahydrophenanthridin–1–yl] acetate
9-(Hydroxymethyl)–6, 6–dimethyl–3–(2–methyloctan–2–yl)–6a, 7, 10, 10a–tetrahydrobenzo[c]chromen–1–ol

Lysergamide
Lysergide and other N-alkyl derivatives of lysergamide
Mescaline
Methcathinone
4–methylmethcathinone
Psilocin
Raw opium
Rolicyclidine
Tenocyclidine
4-Bromo-2,5-dimethoxy-a-methylphenethylamine
N,N-Diethyltryptamine
N,N-Dimethyltryptamine
2,5-Dimethoxy-,4-dimethylphenethylamine
N-Hydroxy-tenamphetamine
4-Methyl-aminorex

(b) any compound (not being a compound for the time being specified in sub-paragraph (a) above) structurally derived from tryptamine or from a ring-hydroxy tryptamine by substitution at the nitrogen atom of the sidechain with one or more alkyl substituents but no other substituent;

(c) the following phenethylamine derivatives, namely -

Allyl(-methyl-3,4-methylenedioxyphenethyl)amine
2-Amino-1-(2,5-dimethoxy-4-methylphenyl)ethanol
2-Amino-1-(3,4-dimethoxyphenyl)ethanol
Benzyl(-methyl-3,4-methylenedioxyphenethyl)amine
4-Bromo-ß,2,5-trimethoxyphenethylamine
N-(4-sec-Butylthio-2,5-dimethoxyphenethyl)hydroxylamine
Cyclopropylmethyl(-methyl-3,4-methylenedioxyphenethyl)amine
2-(4,7-Dimethoxy-2,3-dihydro-1H-indan-5-yl)ethylamine
2-(4,7-Dimethoxy-2,3-dihydro-1H-indan-5-yl)-1-methylethylamine
2-(2,5-Dimethoxy-4-methylphenyl)cyclopropylamine
2-(1,4-Dimethoxy-2-naphthyl)ethylamine
2-(1,4-Dimethoxy-2-naphthyl)-1-methylethylamine
N-(2,5-Dimethoxy-4-propylthiophenethyl)hydroxylamine
2-(1,4-Dimethoxy-5,6,7,8-tetrahydro-2-naphthyl)ethylamine
2-(1,4-Dimethoxy-5,6,7,8-tetrahydro-2-naphthyl)-1-methylethylamine
a,a-Dimethyl-3,4-methylenedioxyphenethylamine
a,a-Dimethyl-3,4-methylenedioxyphenethyl(methyl)amine
Dimethyl(-methyl-3,4-methylenedioxyphenethyl)amine
N-(4-Ethylthio-2,5-dimethoxyphenethyl)hydroxylamine
4-Iodo-2,5-dimethoxy-a-methylphenethyl(dimethyl)amine
2-(1,4-Methano-5,8-dimethoxy-1,2,3,4-tetrahydro-6-naphthyl)ethylamine
2-(1,4-Methano-5,8-dimethoxy-1,2,3,4-tetrahydro-6-naphthyl)-1-methylethylamine
2-(5-Methoxy-2,2-dimethyl-2,3-dihydrobenzo[b]furan-6-yl)-1-methylethylamine
2-Methoxyethyl(-methyl-3,4-methylenedioxyphenethyl)amine
2-(5-Methoxy-2-methyl-2,3-dihydrobenzo[b]furan-6-yl)-1-methylethylamine
ß-Methoxy-3,4-methylenedioxyphenethylamine
1-(3,4-Methylenedioxybenzyl)butyl(ethyl)amine
1-(3,4-Methylenedioxybenzyl)butyl(methyl)amine
2-(-Methyl-3,4-methylenedioxyphenethylamino)ethanol
-Methyl-3,4-methylenedioxyphenethyl(prop-2-ynyl)amine
N-Methyl-N-(-methyl-3,4-methylenedioxyphenethyl)hydroxylamine
O-Methyl-N-(-methyl-3,4-methylenedioxyphenethyl)hydroxylamine
-Methyl-4-(methylthio)phenethylamine
ß,3,4,5-Tetramethoxyphenethylamine
ß,2,5-Trimethoxy-4-methylphenethylamine

(d) any compound (not being methoxyphenamine or a compound for the time being specified in sub-paragraph (a) above) structurally derived from phenethylamine, an N-alkylphenethylamine, -methylphenethylamine, an N-alkyl--methylphenethylamine, -ethylphenethylamine, or an N-alkyl--ethylphenethylamine by substitution in the ring to any extent with alkyl, alkoxy, alkylenedioxy or halide substitutents, whether or not further substituted in the ring by one or more other univalent substituents;

(e) any compound (not being a compound for the time being specified in Schedule 2) structurally derived from fentanyl by modification in any of the following ways, that is to say:

(f) any compound (not being a compound for the time being specified in Schedule 2) structurally derived from pethidine by modification in any of the following ways, that is to say -

(g) 1–benzylpiperazine or any compound (not being a compound for the time being specified in Part II of this Schedule) structurally derived from 1–benzylpiperazine or 1–phenylpiperazine by modification in any of the following ways— .

(h) [2,3–Dihydro–5–methyl–3–(4–morpholinylmethyl)pyrrolo[1, 2, 3–de]–1,4–benzoxazin–6–yl]–1–naphthalenylmethanone; .

(i) 3–Dimethylheptyl–11–hydroxyhexahydrocannabinol; .

(j) [9–Hydroxy–6–methyl–3–[5–phenylpentan–2–yl] oxy–5, 6, 6a, 7, 8, 9, 10, 10a–octahydrophenanthridin–1–yl] acetate; .

(k) 9-(Hydroxymethyl)–6, 6–dimethyl–3–(2–methyloctan–2–yl)–6a, 7, 10, 10a–tetrahydrobenzo[c]chromen–1–ol; .

(l) any compound structurally derived from 3–(1–naphthoyl)indole or 1H–indol–3–yl–(1–naphthyl)methane by substitution at the nitrogen atom of the indole ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent; .

(m) any compound structurally derived from 3–(1–naphthoyl)pyrrole by substitution at the nitrogen atom of the pyrrole ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the pyrrole ring to any extent and whether or not substituted in the naphthyl ring to any extent; .

(n) any compound structurally derived from 1–(1–naphthylmethyl)indene by substitution at the 3–position of the indene ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent; .

(o) any compound structurally derived from 3–phenylacetylindole by substitution at the nitrogen atom of the indole ring with alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent; .

(p) any compound structurally derived from 2–(3–hydroxycyclohexyl)phenol by substitution at the 5–position of the phenolic ring by alkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl or 2–(4–morpholinyl)ethyl, whether or not further substituted in the cyclohexyl ring to any extent.

(q) Any compound (not being bupropion, diethylpropion, pyrovalerone or a compound for the time being specified in sub–paragraph (a) above) structurally derived from 2–amino–1–phenyl–1–propanone by modification in any of the following ways, that is to say, .

(r) Any compound structurally derived from 2–aminopropan–1–one by substitution at the 1-position with any monocyclic, or fused-polycyclic ring system (not being a phenyl ring or alkylenedioxyphenyl ring system), whether or not the compound is further modified in any of the following ways, that is to say, .

2. Any stereoisomeric form of a substance specified in paragraph 1.

3. Any ester or ether of a substance specified in paragraph 1 or 2.

4. Any salt of a substance specified in any of paragraphs 1 to 3.

5. Any preparation or other product containing a substance or product specified in any of paragraphs 1 to 4, not being a preparation specified in Schedule 5.

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Schedule 2

CONTROLLED DRUGS SUBJECT TO THE REQUIREMENTS OF REGULATIONS 14, 15, 16, 18, 19, 20, 21, 23, 26 AND 27

1. The following substances and products, namely-

Acetorphine
Alfentanil
Allylprodine
Alphacetylmethadol
Alphameprodine
Alphamethadol
Alphaprodine
Anileridine

Benzethidine
Benzylmorphine (3-benzylmorphine)
Betacetylmethadol
Betameprodine
Betamethadol
Betaprodine
Bezitramide

Carfentanil
Clonitazene
Cocaine

Desomorphine
Dextromoramide
Diamorphine
Diampromide
Diethylthiambutene
Difenoxin
Dihydrocodeinone O-carboxymethyloxime
Dihydretorphine
Dihydromorphine
Dimenoxadole
Dimepheptanol
Dimethylthiambutene
Dioxaphetyl butyrate
Diphenoxylate
Dipipanone
Dronabinol
Drotebanol

Ecgonine, and any derivative of
ecgonine which is convertible to
ecgonine or to cocaine
Ethylmethylthiambutene
Etonitazene
Etorphine
Etoxeridine

Fentanyl
Furethidine

Hydrocodone
Hydromorphinol
Hydromorphone
Hydroxypethidine

Isomethadone

Ketobemidone

Levomethorphan
Levomoramide
Levophenacylmorphan
Levorphanol
Lofentanil

Medicinal opium
Metazocine
Methadone
Methadyl acetate
Methyldesorphine
Methyldihydromorphine
(6-methyldihydromorphine)
Metopon
Morpheridine
Morphine
Morphine methobromide, morphine N-oxide and
other pentavalent nitrogen morphine derivatives
Myrophine

Nabilone
Nicomorphine
Noracymethadol
Norlevorphanol
Normethadone
Normorphine
Norpipanone

Oxycodone
Oxymorphone

Pethidine
Phenadoxone
Phenampromide
Phenazocine
Phencyclidine
Phenomorphan
Phenoperidine
Piminodine
Piritramide
Proheptazine
Properidine

Racemethorphan
Remifentatil
Racemoramide
Racemorphan

Sufentanil

Thebacon
Thebaine
Tilidate
Trimeperidine

Zipeprol

4-Cyano-2-dimethylamino-4,4-diphenylbutane
4-Cyano-1-methyl-4-phenylpiperidine
2-Methyl-3-morpholino-1,1-diphenylpropane-carboxylic acid
-Methylphenethylhydroxylamine
1-Methyl-4-phenylpiperidine-4-carboxylic acid
4-Phenylpiperidine-4-carboxylic acid ethyl ester

2. Any stereoisomeric form of a substance specified in paragraph 1 not being dextromethorphan or dextrorphan.

3. Any ester or ether of a substance specified in paragraph 1 or 2, not being a substance specified in paragraph 6.

4. Any salt of a substance specified in any of paragraphs 1 to 3.

5. Any preparation or other product containing a substance or product specified in any of paragraphs 1 to 4, not being a preparation specified in Schedule 5.

6. The following substances and products, namely -

Acetyldihydrocodeine
Amphetamine

Codeine

Dextropropoxyphene
Dihydrocodeine

Ethylmorphine (3-ethylmorphine)

Fenethylline

Glutethimide

Lefetamine

Mecloqualone
Methaqualone
Methylamphetamine
Methylphenidate

Nicocodine
Nicodicodine (6-nicotinoyldihydrocodeine)
Norcodeine

Phenmetrazine
Pholcodine
Propiram

Quinalbarbitone

7. Any stereoisomeric form of a substance specified in paragraph 6.

8. Any salt of a substance specified in paragraph 6 or 7.

9. Any preparation or other product containing a substance or product specified in any of paragraphs 6 to 8, not being a preparation specified in Schedule 5.

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Schedule 3

CONTROLLED DRUGS SUBJECT TO THE REQUIREMENTS OF REGULATIONS 14, 15 (EXCEPT TEMAZEPAM), 16, 18, 22, 23, 24, 26 AND 27

The following substances, namely-

Benzphetamine
Buprenorphine

Cathine
Chlorphentermine

Diethylpropion

Ethchlorvynol
Ethinamate

Flunitrazepam

 

Mazindol
Mephentennine
Meprobamate

Methylphenobarbitone
Methyprylone

Pentazocine
Phendimetrazine
Phentermine
Pipradrol

Temazepam

(b) any 5, 5 disubstituted barbituric acid not being quinalbarbitone.
2 Any stereoisomeric form of a substance specified in paragraph 1 not being phenylpropanolamine.
3 Any salt of a substance specified in paragraph 1 or 2.
4 Any preparation or other product containing a substance specified in any of paragraphs 1 to 3, not being a preparation specified in Schedule 5.

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Schedule 4 - Part I

CONTROLLED DRUGS SUBJECT TO THE REQUIREMENTS OF REG ULATIONS 22, 23, 26 AND 27

1. The following substances and products, namely-

Alprazolam
Aminorex

Bromazepam
Brotizolam

Camazepam
Chlordiazepoxide
Clobazam
Clonazepam
Clorazepic acid
Clotiazepam
Cloxazolam
Delorazepam

Diazepam

Estazolam
Ethyl loflazepate

Fencamfamin
Fenproporex
Fludiazepam
Flurazepam

GammahydroxyButyrate (GHB)

Halazepam
Haloxazolam
4-Hydroxy-n-butyric Acid

Ketamine
Ketazolam

Loprazolam
Lorazepam
Lormetazepam

Medazepam
Mefenorex
Mesocarb
Midazolam

Nimetazepam
Nitrazepam
Nordazepam

Oxazepam
Oxazolam

Pemoline
Pinazepam
Prazepam
Pyrovalerone

Tetrazepam
Triazolam

N-Ethylamphetamine

Zolpidem

2. Any stereoisomeric form of a substance specified in paragraph 1.

3. Any salt of a substance specified in paragraph 1 or 2.

4. Any preparation or other product containing a substance or product specified in any of paragraphs 1 to 3, not being a preparation specified in Schedule 5.

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Schedule 4 - Part II

CONTROLLED DRUGS EXCEPTED FROM THE PROHIBITION ON POSSESSION WHEN IN THE FORM OF A MEDICINAL PRODUCT;
EXCLUDED FROM THE APPLICATION OF OFFENCES ARISING FROM THE PROHIBITION ON IMPORTATION AND EXPORTATION WHEN IMPORTED OR EXPORTED IN THE FORM OF A MEDICINAL PRODUCT BY ANY PERSON FOR ADMINISTRATION TO HIMSELF; AND SUBJECT TO THE REQUIREMENTS OF REGULATIONS 22, 23, 26 AND 27

1. The following substances, namely-

5a–Androstane–3,17–diol
Androst-4-ene-3,17-diol
1–Androstenediol
1–Androstenedione

4-Androstene-3, 17-dione
5-Androstenedione
5-Androstene-3, 17-diol
Atamestane
Bolandiol
Bolasterone
Bolazine
Boldenone
Boldione
Bolenol
Bolmantalate
Calusterone
4-Chloromethandienone
Clostebol
Danazol
Desoxymethyltestosterone

Drostanolone
Enestebol
Epitiostanol
Ethyloestrenol
Fluoxymesterone
Formebolone
Furazabol
Gestrinone
3–Hydroxy–5a–androstan–17–one

Mebolazine
Mepitiostane
Mesabolone -
Mesterolone
Methandienone
Methandriol
Mestanolone

Methenolone
Methyltestosterone
Metribolone
Mibolerone
Nandrolone
19–Norandrostenedione
19-Nor-4-Androstene-3, 17-dione
19-Nor-5-Androstene-3, 17-diol
19–Norandrosterone
Norboletone
Norclostebol
Norethandrolone
Ovandrotone
Oxabolone
Oxandrolone
Oxymesterone
Oxymetholone
Prasterone
Propetandrol
Prostanozol
Quinbolone
Roxibolone
Silandrone
Stanolone
Stanozolol
Stenbolone
Testosterone
Tetrahydrogestrinone
Thiomesterone
Trenbolone

2. Any compound (not being Trilostane or a compound for the time being specified in paragraph 1 of this Part of this Schedule) structurally derived from 17-hydroxyandrostan-3-one or from 17-hydroxyestran-3-one by modification in any of the following ways, that is to say -

3. Any substance which is an ester or ether (or, where more than one hydroxyl function is available, both an ester and an ether) of a substance specified in paragraph 1 or described in paragraph 2 of this Part of this Schedule.

4. The following substances, namely:

Chorionic Gonadotrophin (HCG)
Clenbuterol
Non-human chorionic gonadotrophin
Somatotropin
Somatrem
Somatropin
Zeranol
Zilpaterol

5. Any stereoisomeric form of a substance specified or described in any of paragraphs 1 to 4 of this Part of this Schedule.

6. Any salt of a substance specified or described in any of paragraphs 1 to 5 of this Part of this Schedule.

7. Any preparation or other product containing a substance or product specified or described in any of paragraphs 1 to 6 of this Part of this Schedule, not being a preparation specified in Schedule 5.

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Schedule 5

CONTROLLED DRUGS EXCEPTED FROM THE PROHIBITION ON |IMPORTATION, EXPORTATION AND POSSESSION AND SUBJECT TO THE REQUIREMENTS OF REGULATIONS 24 AND 26

1 - (1) Any preparation of one or more of the substances to which this paragraph applies, not being a preparation designed for administration by injection, when compounded with one or more other active or inert ingredients and containing a total of not more than 100 milligrams of the substance or substances (calculated as base) per dosage unit or with a total concentration of not more than 2.5% (calculated as base) in undivided preparations.

(2) The substances to which this paragraph applies are acetyldihydrocodeine, codeine, dihydrocodeine, ethylmorphine, nicocodine, nicodicodine (6-nicotinoyldihydrocodeine), norcodeine and pholcodine and their respective salts.

2. Any preparation of cocaine containing not more than 0.1% of cocaine calculated as cocaine base, being a preparation compounded with one or more other active or inert ingredients in such a way that the cocaine cannot be recovered by readily applicable means or in a yield which would constitute a risk to health.

3. Any preparation of medicinal opium or of morphine containing (in either case) not more than 0.2% of morphine calculated as anhydrous morphine base, being a preparation compounded with one or more other active or inert ingredients in such a way that the opium or, as the case may be, the morphine cannot be recovered by readily applicable means or in a yield which would constitute a risk to health.

4. Any preparation of dextropropoxyphene, being a preparation designed for oral administration, containing not more than 135 milligrams of dextropropoxyphene (calculated as base) per dosage unit or with a total concentration of not more than 2.5% (calculated as base) in undivided preparations.

5. Any preparation of difenoxin containing, per dosage unit, not more than 0.5 milligrams of difenoxin and a quantity ofatropine sulphate equivalent to at least 5% of the dose of difenoxin.

6. Any preparation of diphenoxylate containing, per dosage unit, not more than 2.5 milligrams of diphenoxylate calculated as base, and a quantity of atropine sulphate equivalent to at least 1% of the dose of diphenoxylate.

7. Any preparation of propiram containing, per dosage unit, not more than 100 milligrams of propiram calculated as base and compounded with at least the same amount (by weight) of methylcellulose.

8. Any powder of ipecacuanha and opium comprising-
10% opium, in powder,
10% ipecacuanha root, in powder, well mixed with
80% of any other powdered ingredient containing no controlled drug.

9. Any mixture containing one or more of the preparations specified in paragraphs 1 to 8, being a mixture of which none of the other ingredients is a controlled drug.

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Amendment to the Misuse of Drugs Regulations by Statutory Instrument

The colours below are linked to the drug entries in the tables and lists above to make it easy to see which drugs were added by which SI in the tables above.

SI 2003/3998
These Regulations amend the Misuse of Drugs Regulations 2001 by adding two substances to paragraph 1 of Schedule 2 (controlled drugs subject to the requirements of regulations 14, 15, 16, 18, 19, 20, 21, 23, 26 and 27) two substances to Part I of Schedule 4 (controlled drugs subject to the requirements of regulations 22, 23, 26 and 27) and four substances to Part II of Schedule 4 (controlled drugs excepted from the prohibition on possession when in the form of a medicinal product; excluded from the application of offences arising from the prohibition on importation and exportation when imported or exported in the form of a medicinal product by any person for administration to himself; and subject to the requirements of regulations 22, 23, 26 and 27).

2005/1653
Regulation 2(3) inserts "a fungus containing psilocin or an ester of psilocin" into Schedule 1 to the 2001 Regulations, enabling the Secretary of State to issue a licence under regulation 5 of the 2001 Regulations in respect of the production, supply, offer to supply or possession of those fungi.

SI 2005/3372
These Regulations insert Ketamine into Part 1 of Schedule 4 to the Misuse of Drugs Regulations 2001.

SI2009/3135
This Order amends the Misuse of Drugs (Designation) Order 2001 by inserting into Part 1 of the Schedule to that Order gamma–butyrolactone (GBL), 1,4–butanediol (1,4–BD), 1–benzylpiperazine (BZP) and a group of substituted piperazines and synthetic cannabinoid receptor agonists excluding nabilone. Regulation 3 specifically excludes two substituted piperazines from the designation.

SI 2009/3136
These Regulations insert 1–benzylpiperazine (BZP), all but two of a group of substituted piperazines and the synthetic cannabinoid agonists into Schedule 1 to the Misuse of Drugs Regulations 2001 (“the 2001 Regulations”), save for nabilone which is inserted into Schedule 2 to the 2001 Regulations along with oripavine. The two other substituted piperazines are inserted into Part 1 of Schedule 4 to the 2001 Regulations and 15 anabolic steroids and 2 non-steroidal agents are inserted into Part 2 of that Schedule. The schedule in which a controlled drug is placed primarily affects the extent to which the drug can be lawfully imported, exported, produced, supplied or possessed and dictates the record keeping, labelling and destruction requirements in relation to those drugs.

Gamma–butyrolactone (GBL) and 1,4–butanediol (1,4–BD) are not inserted into any schedule. However, regulation 3 makes it lawful to import, export, produce, supply, offer to supply or possess these substances except where a person does so, knowing or believing that it will be used for the purpose of human ingestion other than as a flavouring in food.

SI 201011/43
This Order amends the Misuse of Drugs (Designation) Order 2001 by inserting into Part 1 of the Schedule to that Order 4-methylmethcathinone (commonly referred to as mephedrone) and other cathinone derivatives.

SI 2010/1144
These Regulations insert 4–methylmethcathinone (commonly referred to as mephedrone) and other cathinone derivatives into Schedule 1 to the Misuse of Drugs Regulations 2001 (“the 2001 Regulations”). The schedule in which a controlled drug is placed primarily affects the extent to which the drug can be lawfully imported, exported, produced, supplied or possessed and dictates the record keeping, labelling and destruction requirements in relation to that drug.

SI2010/1800
This Order amends the Misuse of Drugs (Designation) Order 2001 by inserting into Part 1 of the Schedule to that Order a further group of cathinone derivatives (including naphthylpyrovalerone, commonly known as naphyrone).

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